Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea

Although Q fever is an important zoonotic infection with a worldwide distribution, no human isolates of Coxiella burnetii have been identified in Korea. For the first time, we identified the nucleotide sequence of C. burnetii from a 32-year-old man with an acute febrile illness in Korea. Diagnosis o...

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Detalles Bibliográficos
Autores principales: Lee, Seung Hun, Heo, Jung Yeon, Lee, Hae Kyung, Lee, Yeong Seon, Jeong, Hye Won, Hwang, Seon Do
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2017
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426248/
https://www.ncbi.nlm.nih.gov/pubmed/28480664
http://dx.doi.org/10.3346/jkms.2017.32.6.1038
Descripción
Sumario:Although Q fever is an important zoonotic infection with a worldwide distribution, no human isolates of Coxiella burnetii have been identified in Korea. For the first time, we identified the nucleotide sequence of C. burnetii from a 32-year-old man with an acute febrile illness in Korea. Diagnosis of acute Q fever was confirmed by seroconversion using indirect immunofluorescence antibody assays. Phylogenetic analysis demonstrated high sequence similarity (99.6%–100%) with C. burnetii 16S rRNA sequences identified from the reservoir. These results are the first genetic analysis of C. burnetii in a human case of Q fever in Korea.

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