Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea

Although Q fever is an important zoonotic infection with a worldwide distribution, no human isolates of Coxiella burnetii have been identified in Korea. For the first time, we identified the nucleotide sequence of C. burnetii from a 32-year-old man with an acute febrile illness in Korea. Diagnosis o...

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Autores principales: Lee, Seung Hun, Heo, Jung Yeon, Lee, Hae Kyung, Lee, Yeong Seon, Jeong, Hye Won, Hwang, Seon Do
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2017
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426248/
https://www.ncbi.nlm.nih.gov/pubmed/28480664
http://dx.doi.org/10.3346/jkms.2017.32.6.1038
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author Lee, Seung Hun
Heo, Jung Yeon
Lee, Hae Kyung
Lee, Yeong Seon
Jeong, Hye Won
Hwang, Seon Do
author_facet Lee, Seung Hun
Heo, Jung Yeon
Lee, Hae Kyung
Lee, Yeong Seon
Jeong, Hye Won
Hwang, Seon Do
author_sort Lee, Seung Hun
collection PubMed
description Although Q fever is an important zoonotic infection with a worldwide distribution, no human isolates of Coxiella burnetii have been identified in Korea. For the first time, we identified the nucleotide sequence of C. burnetii from a 32-year-old man with an acute febrile illness in Korea. Diagnosis of acute Q fever was confirmed by seroconversion using indirect immunofluorescence antibody assays. Phylogenetic analysis demonstrated high sequence similarity (99.6%–100%) with C. burnetii 16S rRNA sequences identified from the reservoir. These results are the first genetic analysis of C. burnetii in a human case of Q fever in Korea.
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spelling pubmed-54262482017-06-01 Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea Lee, Seung Hun Heo, Jung Yeon Lee, Hae Kyung Lee, Yeong Seon Jeong, Hye Won Hwang, Seon Do J Korean Med Sci Brief Communication Although Q fever is an important zoonotic infection with a worldwide distribution, no human isolates of Coxiella burnetii have been identified in Korea. For the first time, we identified the nucleotide sequence of C. burnetii from a 32-year-old man with an acute febrile illness in Korea. Diagnosis of acute Q fever was confirmed by seroconversion using indirect immunofluorescence antibody assays. Phylogenetic analysis demonstrated high sequence similarity (99.6%–100%) with C. burnetii 16S rRNA sequences identified from the reservoir. These results are the first genetic analysis of C. burnetii in a human case of Q fever in Korea. The Korean Academy of Medical Sciences 2017-06 2017-03-28 /pmc/articles/PMC5426248/ /pubmed/28480664 http://dx.doi.org/10.3346/jkms.2017.32.6.1038 Text en © 2017 The Korean Academy of Medical Sciences. https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
Lee, Seung Hun
Heo, Jung Yeon
Lee, Hae Kyung
Lee, Yeong Seon
Jeong, Hye Won
Hwang, Seon Do
Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea
title Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea
title_full Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea
title_fullStr Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea
title_full_unstemmed Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea
title_short Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea
title_sort clinical and genetic features of coxiella burnetii in a patient with an acute febrile illness in korea
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426248/
https://www.ncbi.nlm.nih.gov/pubmed/28480664
http://dx.doi.org/10.3346/jkms.2017.32.6.1038
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