Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma

Cell-free circulating tumour DNA (ctDNA) in plasma has been shown to be informative of the genomic alterations present in tumours and has been used to monitor tumour progression and response to treatments. However, patients with brain tumours do not present with or present with low amounts of ctDNA...

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Detalles Bibliográficos
Autores principales: De Mattos-Arruda, Leticia, Mayor, Regina, Ng, Charlotte K. Y., Weigelt, Britta, Martínez-Ricarte, Francisco, Torrejon, Davis, Oliveira, Mafalda, Arias, Alexandra, Raventos, Carolina, Tang, Jiabin, Guerini-Rocco, Elena, Martínez-Sáez, Elena, Lois, Sergio, Marín, Oscar, de la Cruz, Xavier, Piscuoglio, Salvatore, Towers, Russel, Vivancos, Ana, Peg, Vicente, Cajal, Santiago Ramon y, Carles, Joan, Rodon, Jordi, González-Cao, María, Tabernero, Josep, Felip, Enriqueta, Sahuquillo, Joan, Berger, Michael F., Cortes, Javier, Reis-Filho, Jorge S., Seoane, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426516/
https://www.ncbi.nlm.nih.gov/pubmed/26554728
http://dx.doi.org/10.1038/ncomms9839

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