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Lithocholic acid controls adaptive immune responses by inhibition of Th1 activation through the Vitamin D receptor

Bile acids are established signaling molecules next to their role in the intestinal emulsification and uptake of lipids. We here aimed to identify a potential interaction between bile acids and CD4(+) Th cells, which are central in adaptive immune responses. We screened distinct bile acid species fo...

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Detalles Bibliográficos
Autores principales: Pols, Thijs W. H., Puchner, Teresa, Korkmaz, H. Inci, Vos, Mariska, Soeters, Maarten R., de Vries, Carlie J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426628/
https://www.ncbi.nlm.nih.gov/pubmed/28493883
http://dx.doi.org/10.1371/journal.pone.0176715

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