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P2Y(6) receptors are involved in mediating the effect of inactivated avian influenza virus H5N1 on IL-6 & CXCL8 mRNA expression in respiratory epithelium

One of the key pathophysiologies of H5N1 infection is excessive proinflammatory cytokine response (cytokine storm) characterized by increases in IFN-β, TNF-α, IL-6, CXCL10, CCL4, CCL2 and CCL5 in the respiratory tract. H5N1-induced cytokine release can occur via an infection-independent mechanism, h...

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Detalles Bibliográficos
Autores principales:	Huipao, Nawiya, Borwornpinyo, Suparerk, Wiboon-ut, Suwimon, Campbell, Craig R., Lee, Il-Ha, Hiranyachattada, Siriphun, Sukasem, Chonlaphat, Thitithanyanont, Arunee, Pholpramool, Chumpol, Cook, David I., Dinudom, Anuwat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426635/ https://www.ncbi.nlm.nih.gov/pubmed/28494003 http://dx.doi.org/10.1371/journal.pone.0176974

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