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Monte Carlo simulation for scanning technique with scattering foil free electron beam: A proof of concept study

This study investigated the potential of a newly proposed scattering foil free (SFF) electron beam scanning technique for the treatment of skin cancer on the irregular patient surfaces using Monte Carlo (MC) simulation. After benchmarking of the MC simulations, we removed the scattering foil to gene...

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Autores principales: Sung, Wonmo, Park, Jong In, Kim, Jung-in, Carlson, Joel, Ye, Sung-Joon, Park, Jong Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426680/
https://www.ncbi.nlm.nih.gov/pubmed/28493940
http://dx.doi.org/10.1371/journal.pone.0177380
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author Sung, Wonmo
Park, Jong In
Kim, Jung-in
Carlson, Joel
Ye, Sung-Joon
Park, Jong Min
author_facet Sung, Wonmo
Park, Jong In
Kim, Jung-in
Carlson, Joel
Ye, Sung-Joon
Park, Jong Min
author_sort Sung, Wonmo
collection PubMed
description This study investigated the potential of a newly proposed scattering foil free (SFF) electron beam scanning technique for the treatment of skin cancer on the irregular patient surfaces using Monte Carlo (MC) simulation. After benchmarking of the MC simulations, we removed the scattering foil to generate SFF electron beams. Cylindrical and spherical phantoms with 1 cm boluses were generated and the target volume was defined from the surface to 5 mm depth. The SFF scanning technique with 6 MeV electrons was simulated using those phantoms. For comparison, volumetric modulated arc therapy (VMAT) plans were also generated with two full arcs and 6 MV photon beams. When the scanning resolution resulted in a larger separation between beams than the field size, the plan qualities were worsened. In the cylindrical phantom with a radius of 10 cm, the conformity indices, homogeneity indices and body mean doses of the SFF plans (scanning resolution = 1°) vs. VMAT plans were 1.04 vs. 1.54, 1.10 vs. 1.12 and 5 Gy vs. 14 Gy, respectively. Those of the spherical phantom were 1.04 vs. 1.83, 1.08 vs. 1.09 and 7 Gy vs. 26 Gy, respectively. The proposed SFF plans showed superior dose distributions compared to the VMAT plans.
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spelling pubmed-54266802017-05-25 Monte Carlo simulation for scanning technique with scattering foil free electron beam: A proof of concept study Sung, Wonmo Park, Jong In Kim, Jung-in Carlson, Joel Ye, Sung-Joon Park, Jong Min PLoS One Research Article This study investigated the potential of a newly proposed scattering foil free (SFF) electron beam scanning technique for the treatment of skin cancer on the irregular patient surfaces using Monte Carlo (MC) simulation. After benchmarking of the MC simulations, we removed the scattering foil to generate SFF electron beams. Cylindrical and spherical phantoms with 1 cm boluses were generated and the target volume was defined from the surface to 5 mm depth. The SFF scanning technique with 6 MeV electrons was simulated using those phantoms. For comparison, volumetric modulated arc therapy (VMAT) plans were also generated with two full arcs and 6 MV photon beams. When the scanning resolution resulted in a larger separation between beams than the field size, the plan qualities were worsened. In the cylindrical phantom with a radius of 10 cm, the conformity indices, homogeneity indices and body mean doses of the SFF plans (scanning resolution = 1°) vs. VMAT plans were 1.04 vs. 1.54, 1.10 vs. 1.12 and 5 Gy vs. 14 Gy, respectively. Those of the spherical phantom were 1.04 vs. 1.83, 1.08 vs. 1.09 and 7 Gy vs. 26 Gy, respectively. The proposed SFF plans showed superior dose distributions compared to the VMAT plans. Public Library of Science 2017-05-11 /pmc/articles/PMC5426680/ /pubmed/28493940 http://dx.doi.org/10.1371/journal.pone.0177380 Text en © 2017 Sung et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Sung, Wonmo
Park, Jong In
Kim, Jung-in
Carlson, Joel
Ye, Sung-Joon
Park, Jong Min
Monte Carlo simulation for scanning technique with scattering foil free electron beam: A proof of concept study
title Monte Carlo simulation for scanning technique with scattering foil free electron beam: A proof of concept study
title_full Monte Carlo simulation for scanning technique with scattering foil free electron beam: A proof of concept study
title_fullStr Monte Carlo simulation for scanning technique with scattering foil free electron beam: A proof of concept study
title_full_unstemmed Monte Carlo simulation for scanning technique with scattering foil free electron beam: A proof of concept study
title_short Monte Carlo simulation for scanning technique with scattering foil free electron beam: A proof of concept study
title_sort monte carlo simulation for scanning technique with scattering foil free electron beam: a proof of concept study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426680/
https://www.ncbi.nlm.nih.gov/pubmed/28493940
http://dx.doi.org/10.1371/journal.pone.0177380
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