Characterizing the Hot Spots Involved in RON-MSPβ Complex Formation Using In Silico Alanine Scanning Mutagenesis and Molecular Dynamics Simulation

Purpose: Implication of protein-protein interactions (PPIs) in development of many diseases such as cancer makes them attractive for therapeutic intervention and rational drug design. RON (Recepteur d’Origine Nantais) tyrosine kinase receptor has gained considerable attention as promising target in...

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Detalles Bibliográficos
Autores principales: Zarei, Omid, Hamzeh-Mivehroud, Maryam, Benvenuti, Silvia, Ustun-Alkan, Fulya, Dastmalchi, Siavoush
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426727/
https://www.ncbi.nlm.nih.gov/pubmed/28507948
http://dx.doi.org/10.15171/apb.2017.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426727/
https://www.ncbi.nlm.nih.gov/pubmed/28507948
http://dx.doi.org/10.15171/apb.2017.018

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