Voltammetric Determination of Ivabradine Hydrochloride Using Multiwalled Carbon Nanotubes Modified Electrode in Presence of Sodium Dodecyl Sulfate

Purpose: A new sensitive sensor was fabricated for the determination of ivabradine hydrochloride (IH) based on modification with multiwalled carbon nanotubes using sodium dodecyl sulfate as micellar medium to increase the sensitivity. Methods: The electrochemical behavior of IH was studied in Britto...

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Autores principales: Attia, Ali Kamal, Abo-Talib, Nisreen Farouk, Tammam, Marwa Hosny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426728/
https://www.ncbi.nlm.nih.gov/pubmed/28507949
http://dx.doi.org/10.15171/apb.2017.019
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author Attia, Ali Kamal
Abo-Talib, Nisreen Farouk
Tammam, Marwa Hosny
author_facet Attia, Ali Kamal
Abo-Talib, Nisreen Farouk
Tammam, Marwa Hosny
author_sort Attia, Ali Kamal
collection PubMed
description Purpose: A new sensitive sensor was fabricated for the determination of ivabradine hydrochloride (IH) based on modification with multiwalled carbon nanotubes using sodium dodecyl sulfate as micellar medium to increase the sensitivity. Methods: The electrochemical behavior of IH was studied in Britton-Robinson buffer (pH: 2.0-11.0) using cyclic and differential pulse voltammetry. Results: The voltammetric response was linear over the range of 3.984 x 10(-6)-3.475 x 10(-5) mol L(-1). The limits of detection and quantification were found to be 5.160 x 10(-7) and 1.720 x 10-6 mol L(-1), respectively. Conclusion: This method is suitable for determination of IH in tablets and plasma.
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spelling pubmed-54267282017-05-15 Voltammetric Determination of Ivabradine Hydrochloride Using Multiwalled Carbon Nanotubes Modified Electrode in Presence of Sodium Dodecyl Sulfate Attia, Ali Kamal Abo-Talib, Nisreen Farouk Tammam, Marwa Hosny Adv Pharm Bull Research Article Purpose: A new sensitive sensor was fabricated for the determination of ivabradine hydrochloride (IH) based on modification with multiwalled carbon nanotubes using sodium dodecyl sulfate as micellar medium to increase the sensitivity. Methods: The electrochemical behavior of IH was studied in Britton-Robinson buffer (pH: 2.0-11.0) using cyclic and differential pulse voltammetry. Results: The voltammetric response was linear over the range of 3.984 x 10(-6)-3.475 x 10(-5) mol L(-1). The limits of detection and quantification were found to be 5.160 x 10(-7) and 1.720 x 10-6 mol L(-1), respectively. Conclusion: This method is suitable for determination of IH in tablets and plasma. Tabriz University of Medical Sciences 2017-04 2017-04-13 /pmc/articles/PMC5426728/ /pubmed/28507949 http://dx.doi.org/10.15171/apb.2017.019 Text en ©2017 The Authors. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, as long as the original authors and source are cited. No permission is required from the authors or the publishers.
spellingShingle Research Article
Attia, Ali Kamal
Abo-Talib, Nisreen Farouk
Tammam, Marwa Hosny
Voltammetric Determination of Ivabradine Hydrochloride Using Multiwalled Carbon Nanotubes Modified Electrode in Presence of Sodium Dodecyl Sulfate
title Voltammetric Determination of Ivabradine Hydrochloride Using Multiwalled Carbon Nanotubes Modified Electrode in Presence of Sodium Dodecyl Sulfate
title_full Voltammetric Determination of Ivabradine Hydrochloride Using Multiwalled Carbon Nanotubes Modified Electrode in Presence of Sodium Dodecyl Sulfate
title_fullStr Voltammetric Determination of Ivabradine Hydrochloride Using Multiwalled Carbon Nanotubes Modified Electrode in Presence of Sodium Dodecyl Sulfate
title_full_unstemmed Voltammetric Determination of Ivabradine Hydrochloride Using Multiwalled Carbon Nanotubes Modified Electrode in Presence of Sodium Dodecyl Sulfate
title_short Voltammetric Determination of Ivabradine Hydrochloride Using Multiwalled Carbon Nanotubes Modified Electrode in Presence of Sodium Dodecyl Sulfate
title_sort voltammetric determination of ivabradine hydrochloride using multiwalled carbon nanotubes modified electrode in presence of sodium dodecyl sulfate
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426728/
https://www.ncbi.nlm.nih.gov/pubmed/28507949
http://dx.doi.org/10.15171/apb.2017.019
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AT tammammarwahosny voltammetricdeterminationofivabradinehydrochlorideusingmultiwalledcarbonnanotubesmodifiedelectrodeinpresenceofsodiumdodecylsulfate

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