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The Challenges of Recombinant Endostatin in Clinical Application: Focus on the Different Expression Systems and Molecular Bioengineering

Angiogenesis plays an essential role in rapid growing and metastasis of the tumors. Inhibition of angiogenesis is a putative strategy for cancer therapy. Endostatin (Es) is an attractive anti-angiogenesis protein with some clinical application challenges including; short half-life, instability in se...

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Detalles Bibliográficos
Autores principales: Mohajeri, Abbas, Sanaei, Sarvin, Kiafar, Farhad, Fattahi, Amir, Khalili, Majid, Zarghami, Nosratollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426730/
https://www.ncbi.nlm.nih.gov/pubmed/28507934
http://dx.doi.org/10.15171/apb.2017.004