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Dysregulation of INF2-mediated mitochondrial fission in SPOP-mutated prostate cancer

Next-generation sequencing of the exome and genome of prostate cancers has identified numerous genetic alternations. SPOP (Speckle-type POZ Protein) was one of the most frequently mutated genes in primary prostate cancer, suggesting SPOP is a potential driver of prostate cancer development and progr...

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Detalles Bibliográficos
Autores principales: Jin, Xiaofeng, Wang, Jie, Gao, Kun, Zhang, Pingzhao, Yao, Longfang, Tang, Yan, Tang, Lisha, Ma, Jian, Xiao, Jiantao, Zhang, Enceng, Zhu, Jie, Zhang, Bin, Zhao, Shi-min, Li, Yao, Ren, Shancheng, Huang, Haojie, Yu, Long, Wang, Chenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426793/
https://www.ncbi.nlm.nih.gov/pubmed/28448495
http://dx.doi.org/10.1371/journal.pgen.1006748