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Dysregulation of INF2-mediated mitochondrial fission in SPOP-mutated prostate cancer
Next-generation sequencing of the exome and genome of prostate cancers has identified numerous genetic alternations. SPOP (Speckle-type POZ Protein) was one of the most frequently mutated genes in primary prostate cancer, suggesting SPOP is a potential driver of prostate cancer development and progr...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426793/ https://www.ncbi.nlm.nih.gov/pubmed/28448495 http://dx.doi.org/10.1371/journal.pgen.1006748 |