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NLRX1 negatively modulates type I IFN to facilitate KSHV reactivation from latency
Kaposi’s sarcoma-associated herpesvirus (KSHV) is a herpesvirus that is linked to Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL) and multicentric Castleman’s disease (MCD). KSHV establishes persistent latent infection in the human host. KSHV undergoes periods of spontaneous reactivation wher...
Autores principales: | Ma, Zhe, Hopcraft, Sharon E., Yang, Fan, Petrucelli, Alex, Guo, Haitao, Ting, Jenny P-Y, Dittmer, Dirk P., Damania, Blossom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426799/ https://www.ncbi.nlm.nih.gov/pubmed/28459883 http://dx.doi.org/10.1371/journal.ppat.1006350 |
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