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Novel signal peptides improve the secretion of recombinant Staphylococcus aureus Alpha toxin(H35L) in Escherichia coli
Secretion of heterologous proteins into Escherichia coli cell culture medium offers significant advantages for downstream processing over production as inclusion bodies; including cost and time savings, and reduction of endotoxin. Signal peptides play an important role in targeting proteins for tran...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427057/ https://www.ncbi.nlm.nih.gov/pubmed/28497288 http://dx.doi.org/10.1186/s13568-017-0394-1 |