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The role of high airway pressure and dynamic strain on ventilator-induced lung injury in a heterogeneous acute lung injury model

BACKGROUND: Acute respiratory distress syndrome causes a heterogeneous lung injury with normal and acutely injured lung tissue in the same lung. Improperly adjusted mechanical ventilation can exacerbate ARDS causing a secondary ventilator-induced lung injury (VILI). We hypothesized that a peak airwa...

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Detalles Bibliográficos
Autores principales: Jain, Sumeet V., Kollisch-Singule, Michaela, Satalin, Joshua, Searles, Quinn, Dombert, Luke, Abdel-Razek, Osama, Yepuri, Natesh, Leonard, Antony, Gruessner, Angelika, Andrews, Penny, Fazal, Fabeha, Meng, Qinghe, Wang, Guirong, Gatto, Louis A., Habashi, Nader M., Nieman, Gary F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427060/
https://www.ncbi.nlm.nih.gov/pubmed/28497420
http://dx.doi.org/10.1186/s40635-017-0138-1