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The LRRC8A Mediated “Swell Activated” Chloride Conductance Is Dispensable for Vacuolar Homeostasis in Neutrophils
The dialysis of human and mouse neutrophils in patch clamp experiments in the conventional whole-cell mode induces the emergence of a chloride (Cl(-)) current that appeared to be primarily regulated by cytoplasmic ionic strength. The characteristics of this current resembled that of the classical, a...
Autores principales: | Behe, Philippe, Foote, Juliet R., Levine, Adam P., Platt, Craig D., Chou, Janet, Benavides, Fernando, Geha, Raif S., Segal, Anthony W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427109/ https://www.ncbi.nlm.nih.gov/pubmed/28553230 http://dx.doi.org/10.3389/fphar.2017.00262 |
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