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Integrated Analysis of DNA Methylation and mRNA Expression Profiles to Identify Key Genes in Severe Oligozoospermia

Severe oligozoospermia (SO) is a complex disorder, whose etiology is the combined effect of genetic factors and epigenetic conditions. In this study, we examined DNA methylation and mRNA expression status in a set of testicular tissues of SO patients (n = 3), and compared methylated data with those...

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Detalles Bibliográficos
Autores principales: Li, Zhiming, Zhuang, Xuan, Zeng, Jinxiong, Tzeng, Chi-Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427114/
https://www.ncbi.nlm.nih.gov/pubmed/28553232
http://dx.doi.org/10.3389/fphys.2017.00261