High level of miR-196b at newly diagnosed pediatric acute myeloid leukemia predicts a poor outcome

Differential expression of microRNAs (miRNAs) has been implicated in leukemogenesis. We investigate the expression pattern of miR-196b. Using quantitative real-time PCR (qRT-PCR), we detected the expression of miR-196b and its correlated genes (SMC1A/MLH1) in initial pediatric AML. A significant ass...

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Detalles Bibliográficos
Autores principales: Xu, Lihua, Guo, Yang, Yan, Wenying, Cen, Jiannong, Niu, Yuna, Yan, Qing, He, Hailong, Chen, Chien-Shing, Hu, Shaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427473/
https://www.ncbi.nlm.nih.gov/pubmed/28507466
http://dx.doi.org/10.17179/excli2016-707

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