Matrix metalloproteinase 9-dependent Notch signaling contributes to kidney fibrosis through peritubular endothelial–mesenchymal transition

Background: Endothelial cells are known to contribute to kidney fibrosis via endothelial–mesenchymal transition (EndoMT). Matrix metalloproteinase 9 (MMP-9) is known to be profibrotic. However, whether MMP-9 contributes to kidney fibrosis via EndoMT is unknown. Methods: Primary mouse renal peritubul...

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Detalles Bibliográficos
Autores principales: Zhao, Ye, Qiao, Xi, Tan, Thian Kui, Zhao, Hong, Zhang, Yun, Liu, Lixin, Zhang, Jianlin, Wang, Lihua, Cao, Qi, Wang, Yiping, Wang, Ya, Wang, Yuan Min, Lee, Vincent W.S., Alexander, Stephen I., Harris, David C.H., Zheng, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427520/
https://www.ncbi.nlm.nih.gov/pubmed/27566305
http://dx.doi.org/10.1093/ndt/gfw308

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