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PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy

BACKGROUND: Nutrient deprivation, hypoxia, radiotherapy and chemotherapy induce endoplasmic reticulum (ER) stress, which activates the so-called unfolded protein response (UPR). Extensive and acute ER stress directs the UPR towards activation of death-triggering pathways. Cancer cells are selected t...

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Detalles Bibliográficos
Autores principales:	Salaroglio, Iris C., Panada, Elisa, Moiso, Enrico, Buondonno, Ilaria, Provero, Paolo, Rubinstein, Menachem, Kopecka, Joanna, Riganti, Chiara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427528/ https://www.ncbi.nlm.nih.gov/pubmed/28499449 http://dx.doi.org/10.1186/s12943-017-0657-0

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