Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohn’s disease, and clinical prognosis in inflammatory bowel disease

BACKGROUND: Cathelicidin (LL-37) is an antimicrobial peptide known to be associated with various autoimmune diseases. We attempt to determine if cathelicidin can accurately reflect IBD disease activity. We hypothesize that serum cathelicidin correlates with mucosal disease activity, stricture, and c...

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Detalles Bibliográficos
Autores principales: Tran, Diana Hoang-Ngoc, Wang, Jiani, Ha, Christina, Ho, Wendy, Mattai, S. Anjani, Oikonomopoulos, Angelos, Weiss, Guy, Lacey, Precious, Cheng, Michelle, Shieh, Christine, Mussatto, Caroline C., Ho, Samantha, Hommes, Daniel, Koon, Hon Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427565/
https://www.ncbi.nlm.nih.gov/pubmed/28494754
http://dx.doi.org/10.1186/s12876-017-0619-4

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