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YidC and SecYEG form a heterotetrameric protein translocation channel

The heterotrimeric SecYEG complex cooperates with YidC to facilitate membrane protein insertion by an unknown mechanism. Here we show that YidC contacts the interior of the SecY channel resulting in a ligand-activated and voltage-dependent complex with distinct ion channel characteristics. The SecYE...

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Detalles Bibliográficos
Autores principales:	Sachelaru, Ilie, Winter, Lukas, Knyazev, Denis G., Zimmermann, Mirjam, Vogt, Andreas, Kuttner, Roland, Ollinger, Nicole, Siligan, Christine, Pohl, Peter, Koch, Hans-Georg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427846/ https://www.ncbi.nlm.nih.gov/pubmed/28273911 http://dx.doi.org/10.1038/s41598-017-00109-8

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