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Postnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection
The strong age dependency of neonatal systemic infection with Escherichia coli K1 can be replicated in the neonatal rat. Gastrointestinal (GI) colonization of two-day-old (P2) rats leads to invasion of the blood within 48 h of initiation of colonization; pups become progressively less susceptible to...
Autores principales: | Birchenough, George M. H., Dalgakiran, Fatma, Witcomb, Luci A., Johansson, Malin E. V., McCarthy, Alex J., Hansson, Gunnar C., Taylor, Peter W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427930/ https://www.ncbi.nlm.nih.gov/pubmed/28250440 http://dx.doi.org/10.1038/s41598-017-00123-w |
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