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Postnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection

The strong age dependency of neonatal systemic infection with Escherichia coli K1 can be replicated in the neonatal rat. Gastrointestinal (GI) colonization of two-day-old (P2) rats leads to invasion of the blood within 48 h of initiation of colonization; pups become progressively less susceptible to...

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Detalles Bibliográficos
Autores principales: Birchenough, George M. H., Dalgakiran, Fatma, Witcomb, Luci A., Johansson, Malin E. V., McCarthy, Alex J., Hansson, Gunnar C., Taylor, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427930/
https://www.ncbi.nlm.nih.gov/pubmed/28250440
http://dx.doi.org/10.1038/s41598-017-00123-w

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