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Usp7-dependent histone H3 deubiquitylation regulates maintenance of DNA methylation

Uhrf1-dependent histone H3 ubiquitylation plays a crucial role in the maintenance of DNA methylation via the recruitment of the DNA methyltransferase Dnmt1 to DNA methylation sites. However, the involvement of deubiquitylating enzymes (DUBs) targeting ubiquitylated histone H3 in the maintenance of D...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Luna, Nishiyama, Atsuya, Misaki, Toshinori, Johmura, Yoshikazu, Ueda, Jun, Arita, Kyohei, Nagao, Koji, Obuse, Chikashi, Nakanishi, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427934/
https://www.ncbi.nlm.nih.gov/pubmed/28246399
http://dx.doi.org/10.1038/s41598-017-00136-5