Galactose and its Metabolites Deteriorate Metaphase II Mouse Oocyte Quality and Subsequent Embryo Development by Disrupting the Spindle Structure

Premature ovarian insufficiency (POI) is a frequent long-term complication of classic galactosemia. The majority of women with this disorder develop POI, however rare spontaneous pregnancies have been reported. Here, we evaluate the effect of D-galactose and its metabolites, galactitol and galactose...

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Detalles Bibliográficos
Autores principales: Thakur, Mili, Shaeib, Faten, Khan, Sana N., Kohan-Ghadr, Hamid-Reza, Jeelani, Roohi, Aldhaheri, Sarah R., Gonik, Bernard, Abu-Soud, Husam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427935/
https://www.ncbi.nlm.nih.gov/pubmed/28331195
http://dx.doi.org/10.1038/s41598-017-00159-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427935/
https://www.ncbi.nlm.nih.gov/pubmed/28331195
http://dx.doi.org/10.1038/s41598-017-00159-y

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