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Methionine aminopeptidase 2 is a key regulator of apoptotic like cell death in Leishmania donovani

We investigate the role of methionine aminopeptidase 2 (MAP2) in miltefosine induced programmed cell death (PCD) in promastigote form of L. donovani. We report that TNP-470, an inhibitor of MAP2, inhibits programmed cell death in miltefosine treated promastigotes. It inhibits the biochemical feature...

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Detalles Bibliográficos
Autores principales:	Kumar, Ritesh, Tiwari, Kartikeya, Dubey, Vikash Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427942/ https://www.ncbi.nlm.nih.gov/pubmed/28273904 http://dx.doi.org/10.1038/s41598-017-00186-9

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