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New role of ventricular assist devices as bridge to transplantation: European perspective

PURPOSE OF REVIEW: Progress of ventricular assist devices (VAD) technology led to improved survival and apparently low morbidity. However, from the European perspective, updated analysis of EUROMACS reveals a somewhat less impressive picture with respect to mortality and morbidity. RECENT FINDINGS:...

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Detalles Bibliográficos
Autores principales: Reineke, David C., Mohacsi, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427991/
https://www.ncbi.nlm.nih.gov/pubmed/28362668
http://dx.doi.org/10.1097/MOT.0000000000000412
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author Reineke, David C.
Mohacsi, Paul J.
author_facet Reineke, David C.
Mohacsi, Paul J.
author_sort Reineke, David C.
collection PubMed
description PURPOSE OF REVIEW: Progress of ventricular assist devices (VAD) technology led to improved survival and apparently low morbidity. However, from the European perspective, updated analysis of EUROMACS reveals a somewhat less impressive picture with respect to mortality and morbidity. RECENT FINDINGS: We describe the great demand of cardiac allografts versus the lack of donors, which is larger in Europe than in the United States. Technical progress of VADs made it possible to work out a modern algorithm of bridge-to-transplant, which is tailored to the need of the particular patient. We analyze the burden of patients undergoing bridge-to-transplant therapy. They are condemned to an intermediate step, coupled with additional major surgery and potential adverse events during heart transplantation. SUMMARY: Based on current registry data, we do have to question the increasingly popular opinion, that the concept of heart transplantation is futureless, which seems to be for someone who treats and compares both patients (VAD and heart transplantation) in daily practice, questionable. Up to now, left ventricular assist device therapy remains a bridge to a better future, which means a bridge to technical innovations or to overcome the dramatic lack of donors in Europe.
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spelling pubmed-54279912017-05-22 New role of ventricular assist devices as bridge to transplantation: European perspective Reineke, David C. Mohacsi, Paul J. Curr Opin Organ Transplant THORACIC TRANSPLANTATION: Edited by Andreas Zuckermann PURPOSE OF REVIEW: Progress of ventricular assist devices (VAD) technology led to improved survival and apparently low morbidity. However, from the European perspective, updated analysis of EUROMACS reveals a somewhat less impressive picture with respect to mortality and morbidity. RECENT FINDINGS: We describe the great demand of cardiac allografts versus the lack of donors, which is larger in Europe than in the United States. Technical progress of VADs made it possible to work out a modern algorithm of bridge-to-transplant, which is tailored to the need of the particular patient. We analyze the burden of patients undergoing bridge-to-transplant therapy. They are condemned to an intermediate step, coupled with additional major surgery and potential adverse events during heart transplantation. SUMMARY: Based on current registry data, we do have to question the increasingly popular opinion, that the concept of heart transplantation is futureless, which seems to be for someone who treats and compares both patients (VAD and heart transplantation) in daily practice, questionable. Up to now, left ventricular assist device therapy remains a bridge to a better future, which means a bridge to technical innovations or to overcome the dramatic lack of donors in Europe. Lippincott Williams & Wilkins 2017-06 2017-05-17 /pmc/articles/PMC5427991/ /pubmed/28362668 http://dx.doi.org/10.1097/MOT.0000000000000412 Text en Copyright © 2017 The Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle THORACIC TRANSPLANTATION: Edited by Andreas Zuckermann
Reineke, David C.
Mohacsi, Paul J.
New role of ventricular assist devices as bridge to transplantation: European perspective
title New role of ventricular assist devices as bridge to transplantation: European perspective
title_full New role of ventricular assist devices as bridge to transplantation: European perspective
title_fullStr New role of ventricular assist devices as bridge to transplantation: European perspective
title_full_unstemmed New role of ventricular assist devices as bridge to transplantation: European perspective
title_short New role of ventricular assist devices as bridge to transplantation: European perspective
title_sort new role of ventricular assist devices as bridge to transplantation: european perspective
topic THORACIC TRANSPLANTATION: Edited by Andreas Zuckermann
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427991/
https://www.ncbi.nlm.nih.gov/pubmed/28362668
http://dx.doi.org/10.1097/MOT.0000000000000412
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