Chronic exposure to low doses of estradiol-17ß increases blood pressure in young female rats: A possible role for central Endothelin-1

Previously, we demonstrated that chronic exposure to low levels of estradiol-17β (E2) increases mean arterial pressure (MAP) in young female Sprague-Dawley (SD) rats, however, the underlying mechanisms are unclear. Since endothelin-1 (ET-1) is implicated in blood pressure (BP) regulation, we hypothe...

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Detalles Bibliográficos
Autores principales: Subramanian, Madhan, MohanKumar, Sheba M. J., Balasubramanian, Priya, Northcott, Carrie A., Garver, Hannah, Fink, Gregory D., MohanKumar, P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428019/
https://www.ncbi.nlm.nih.gov/pubmed/28273940
http://dx.doi.org/10.1038/s41598-017-00213-9

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