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Remote control of glucose homeostasis in vivo using photopharmacology
Photopharmacology describes the use of light to precisely deliver drug activity in space and time. Such approaches promise to improve drug specificity by reducing off-target effects. As a proof-of-concept, we have subjected the fourth generation photoswitchable sulfonylurea JB253 to comprehensive to...
Autores principales: | Mehta, Zenobia B., Johnston, Natalie R., Nguyen-Tu, Marie-Sophie, Broichhagen, Johannes, Schultz, Peter, Larner, Dean P., Leclerc, Isabelle, Trauner, Dirk, Rutter, Guy A., Hodson, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428208/ https://www.ncbi.nlm.nih.gov/pubmed/28331198 http://dx.doi.org/10.1038/s41598-017-00397-0 |
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