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Regulation of membrane ruffling by polarized STIM1 and ORAI1 in cortactin-rich domains

Cell motility and migration requires the reorganization of the cortical cytoskeleton at the leading edge of cells and extracellular Ca(2+) entry is essential for this reorganization. However the molecular nature of the regulators of this pathway is unknown. This work contributes to understanding the...

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Detalles Bibliográficos
Autores principales: Lopez-Guerrero, Aida M., Tomas-Martin, Patricia, Pascual-Caro, Carlos, Macartney, Thomas, Rojas-Fernandez, Alejandro, Ball, Graeme, Alessi, Dario R., Pozo-Guisado, Eulalia, Martin-Romero, Francisco Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428229/
https://www.ncbi.nlm.nih.gov/pubmed/28341841
http://dx.doi.org/10.1038/s41598-017-00331-4