Cargando…

Fgf21 regulates T-cell development in the neonatal and juvenile thymus

We have previously shown that Fibroblast growth factor 21 (Fgf21) is expressed in the thymus as well as in the liver. In line with this expression profile, Fgf21 was recently reported to protect against ageing-related thymic senescence by improving the function of thymic epithelial cells (TECs). How...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakayama, Yoshiaki, Masuda, Yuki, Ohta, Hiroya, Tanaka, Tomohiro, Washida, Miwa, Nabeshima, Yo-ichi, Miyake, Ayumi, Itoh, Nobuyuki, Konishi, Morichika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428243/ https://www.ncbi.nlm.nih.gov/pubmed/28336912 http://dx.doi.org/10.1038/s41598-017-00349-8

Ejemplares similares

Roles of FGF Signals in Heart Development, Health, and Disease
por: Itoh, Nobuyuki, et al.
Publicado: (2016)

Fgf16 Is Required for Specification of GABAergic Neurons and Oligodendrocytes in the Zebrafish Forebrain
por: Miyake, Ayumi, et al.
Publicado: (2014)

Fgf21 Impairs Adipocyte Insulin Sensitivity in Mice Fed a Low-Carbohydrate, High-Fat Ketogenic Diet
por: Murata, Yusuke, et al.
Publicado: (2013)

FGF21 as an Endocrine Regulator in Lipid Metabolism: From Molecular Evolution to Physiology and Pathophysiology
por: Murata, Yusuke, et al.
Publicado: (2011)

Endocrine FGFs: Evolution, Physiology, Pathophysiology, and Pharmacotherapy
por: Itoh, Nobuyuki, et al.
Publicado: (2015)

Angiotensin II-induced cardiac hypertrophy and fibrosis are promoted in mice lacking Fgf16
por: Matsumoto, Emi, et al.
Publicado: (2013)

Fgf22 regulated by Fgf3/Fgf8 signaling is required for zebrafish midbrain development
por: Miyake, Ayumi, et al.
Publicado: (2013)

Neudesin as a unique secreted protein with multi-functional roles in neural functions, energy metabolism, and tumorigenesis
por: Ohta, Hiroya, et al.
Publicado: (2015)

Roles of FGFs As Paracrine or Endocrine Signals in Liver Development, Health, and Disease
por: Itoh, Nobuyuki, et al.
Publicado: (2016)

Pathophysiological roles of FGF signaling in the heart
por: Itoh, Nobuyuki, et al.
Publicado: (2013)

Roles of FGF20 in dopaminergic neurons and Parkinson's disease
por: Itoh, Nobuyuki, et al.
Publicado: (2013)

CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms
por: Satoh, Aoi, et al.
Publicado: (2020)

Neurotrophic effects of neudesin in the central nervous system
por: Kimura, Ikuo, et al.
Publicado: (2013)

Brorin is required for neurogenesis, gliogenesis, and commissural axon guidance in the zebrafish forebrain
por: Miyake, Ayumi, et al.
Publicado: (2017)

FGF21 as a Hepatokine, Adipokine, and Myokine in Metabolism and Diseases
por: Itoh, Nobuyuki
Publicado: (2014)

Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood
por: Yuan, Xunmei, et al.
Publicado: (2018)

Antitumor activity of orally administered maitake α-glucan by stimulating antitumor immune response in murine tumor
por: Masuda, Yuki, et al.
Publicado: (2017)

Calpain 1 inhibitor BDA-410 ameliorates α-klotho-deficiency phenotypes resembling human aging-related syndromes
por: Nabeshima, Yoko, et al.
Publicado: (2014)

Deletion of the Neurotrophic Factor neudesin Prevents Diet-induced Obesity by Increased Sympathetic Activity
por: Ohta, Hiroya, et al.
Publicado: (2015)

Feto-maternal cholesterol transport regulated by β-Klotho–FGF15 axis is essential for fetal growth
por: Kobayashi, Kanako, et al.
Publicado: (2023)

Roles of FGFs as Adipokines in Adipose Tissue Development, Remodeling, and Metabolism
por: Ohta, Hiroya, et al.
Publicado: (2014)

Caveolin-1 Promotes Early Neuronal Maturation via Caveolae-Independent Trafficking of N-Cadherin and L1
por: Shikanai, Mima, et al.
Publicado: (2018)

Rab21 regulates caveolin‐1‐mediated endocytic trafficking to promote immature neurite pruning
por: Shikanai, Mima, et al.
Publicado: (2023)

Pemafibrate Prevents Retinal Pathological Neovascularization by Increasing FGF21 Level in a Murine Oxygen-Induced Retinopathy Model
por: Tomita, Yohei, et al.
Publicado: (2019)

FGF19 subfamily members: FGF19 and FGF21
por: Dolegowska, Katarzyna, et al.
Publicado: (2019)

Paradoxical Regulation of Human FGF21 by Both Fasting and Feeding Signals: Is FGF21 a Nutritional Adaptation Factor?
por: Uebanso, Takashi, et al.
Publicado: (2011)

Single ingestion of soy β-conglycinin induces increased postprandial circulating FGF21 levels exerting beneficial health effects
por: Hashidume, Tsutomu, et al.
Publicado: (2016)

Morphological and Molecular Basis of Cytoplasmic Dilation and Swelling in Cortical Migrating Neurons
por: Nishimura, Yoshiaki V., et al.
Publicado: (2017)

FGF19 and FGF21: In NASH we trust
por: Talukdar, Saswata, et al.
Publicado: (2020)

FGF21 and Cardiac Physiopathology
por: Planavila, Anna, et al.
Publicado: (2015)

Fundamentals of FGF19 & FGF21 Action In Vitro and In Vivo
por: Adams, Andrew C., et al.
Publicado: (2012)

FGF19 and FGF21 for the Treatment of NASH—Two Sides of the Same Coin? Differential and Overlapping Effects of FGF19 and FGF21 From Mice to Human
por: Henriksson, Emma, et al.
Publicado: (2020)

Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue
por: Villarroya, Joan, et al.
Publicado: (2018)

Fibroblast Growth Factor 21 (FGF21) in Human Cerebrospinal Fluid: Relationship With Plasma FGF21 and Body Adiposity
por: Tan, Bee K., et al.
Publicado: (2011)

Ultrastructural study of the thymus of Mugil liza Valenciennes, 1836 juveniles
por: de Medeiros, Ane Felice Frâncio, et al.
Publicado: (2020)

Discovery of α-Klotho unveiled new insights into calcium and phosphate homeostasis
por: Nabeshima, Yo-ichi
Publicado: (2009)

FGF21 as a Stress Hormone: The Roles of FGF21 in Stress Adaptation and the Treatment of Metabolic Diseases
por: Kim, Kook Hwan, et al.
Publicado: (2014)

Membrane progesterone receptor beta (mPRβ/Paqr8) promotes progesterone-dependent neurite outgrowth in PC12 neuronal cells via non-G protein-coupled receptor (GPCR) signaling
por: Kasubuchi, Mayu, et al.
Publicado: (2017)

Head Over Hepatocytes for FGF21
por: Potthoff, Matthew J., et al.
Publicado: (2014)

Analysis of Functional Promoter of Camel FGF21 Gene and Identification of Small Compounds Targeting FGF21 Protein
por: Yong, Fang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9f806lfm5i9mca0iv6g7rn1gbj