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A Biologically-validated HCV E1E2 Heterodimer Structural Model
The design of vaccine strategies and the development of drugs targeting the early stages of Hepatitis C virus (HCV) infection are hampered by the lack of structural information about its surface glycoproteins E1 and E2, the two constituents of HCV entry machinery. Despite the recent crystal resoluti...
Autores principales: | Castelli, Matteo, Clementi, Nicola, Pfaff, Jennifer, Sautto, Giuseppe A., Diotti, Roberta A., Burioni, Roberto, Doranz, Benjamin J., Dal Peraro, Matteo, Clementi, Massimo, Mancini, Nicasio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428263/ https://www.ncbi.nlm.nih.gov/pubmed/28303031 http://dx.doi.org/10.1038/s41598-017-00320-7 |
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