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The role of axonal Kv1 channels in CA3 pyramidal cell excitability

Axonal ion channels control spike initiation and propagation along the axon and determine action potential waveform. We show here that functional suppression of axonal Kv1 channels with local puff of dendrotoxin (DTx), laser or mechanical axotomy significantly increased excitability measured in the...

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Detalles Bibliográficos
Autores principales: Rama, Sylvain, Zbili, Mickael, Fékété, Aurélie, Tapia, Mónica, Benitez, Maria José, Boumedine, Norah, Garrido, Juan José, Debanne, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428268/
https://www.ncbi.nlm.nih.gov/pubmed/28331203
http://dx.doi.org/10.1038/s41598-017-00388-1

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