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The relationship between retinal nerve fibre layer thickness profiles and CorvisST tonometry measured biomechanical properties in young healthy subjects

We previously reported that a shallow circumpapillary retinal nerve fiber layer (cpRNFL) peak angle as measured by optical coherence tomography (OCT) suggests the temporal retina is stretched around the optic disc from the papillo-macular bundle (Yamashita T et al. Investigative Ophthalmol Vis Sci 2...

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Autores principales: Matsuura, Masato, Murata, Hiroshi, Nakakura, Shunsuke, Nakao, Yoshitaka, Yamashita, Takehiro, Hirasawa, Kazunori, Fujino, Yuri, Kiuchi, Yoshiaki, Asaoka, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428286/
https://www.ncbi.nlm.nih.gov/pubmed/28341831
http://dx.doi.org/10.1038/s41598-017-00345-y
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author Matsuura, Masato
Murata, Hiroshi
Nakakura, Shunsuke
Nakao, Yoshitaka
Yamashita, Takehiro
Hirasawa, Kazunori
Fujino, Yuri
Kiuchi, Yoshiaki
Asaoka, Ryo
author_facet Matsuura, Masato
Murata, Hiroshi
Nakakura, Shunsuke
Nakao, Yoshitaka
Yamashita, Takehiro
Hirasawa, Kazunori
Fujino, Yuri
Kiuchi, Yoshiaki
Asaoka, Ryo
author_sort Matsuura, Masato
collection PubMed
description We previously reported that a shallow circumpapillary retinal nerve fiber layer (cpRNFL) peak angle as measured by optical coherence tomography (OCT) suggests the temporal retina is stretched around the optic disc from the papillo-macular bundle (Yamashita T et al. Investigative Ophthalmol Vis Sci 2013). The purpose of the current study was to investigate the relationship between CorvisST tonometry (CST) corneal measurements, axial length (AL) and the change in OCT-measured cpRNFL peak angle, in young healthy subjects. OCT and CST measurements were carried out in 97 eyes of 97 young healthy volunteers. The relationship between cpRNFL peak angle and 12 CST parameters, adjusted for AL, was investigated using linear modelling. The mean ± standard deviation cpRNFL peak angle of the 97 healthy volunteers was 130.6 ± 25.4 (range: 77.8 to 207.0) degrees. The optimal linear model to explain cpRNFL peak angle (chosen from 2(16) different models) included three CST variables related to the speed and size of energy absorption (namely, A1 time, A1 length and A2 time), in addition to AL. In eyes with longer AL and shorter energy absorption in CST measurement, temporal retina is stretched around the optic disc from the papillo-macular bundle, as suggested by a shallow cpRNFL peak angle.
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spelling pubmed-54282862017-05-15 The relationship between retinal nerve fibre layer thickness profiles and CorvisST tonometry measured biomechanical properties in young healthy subjects Matsuura, Masato Murata, Hiroshi Nakakura, Shunsuke Nakao, Yoshitaka Yamashita, Takehiro Hirasawa, Kazunori Fujino, Yuri Kiuchi, Yoshiaki Asaoka, Ryo Sci Rep Article We previously reported that a shallow circumpapillary retinal nerve fiber layer (cpRNFL) peak angle as measured by optical coherence tomography (OCT) suggests the temporal retina is stretched around the optic disc from the papillo-macular bundle (Yamashita T et al. Investigative Ophthalmol Vis Sci 2013). The purpose of the current study was to investigate the relationship between CorvisST tonometry (CST) corneal measurements, axial length (AL) and the change in OCT-measured cpRNFL peak angle, in young healthy subjects. OCT and CST measurements were carried out in 97 eyes of 97 young healthy volunteers. The relationship between cpRNFL peak angle and 12 CST parameters, adjusted for AL, was investigated using linear modelling. The mean ± standard deviation cpRNFL peak angle of the 97 healthy volunteers was 130.6 ± 25.4 (range: 77.8 to 207.0) degrees. The optimal linear model to explain cpRNFL peak angle (chosen from 2(16) different models) included three CST variables related to the speed and size of energy absorption (namely, A1 time, A1 length and A2 time), in addition to AL. In eyes with longer AL and shorter energy absorption in CST measurement, temporal retina is stretched around the optic disc from the papillo-macular bundle, as suggested by a shallow cpRNFL peak angle. Nature Publishing Group UK 2017-03-24 /pmc/articles/PMC5428286/ /pubmed/28341831 http://dx.doi.org/10.1038/s41598-017-00345-y Text en © The Author(s) 2017 This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Matsuura, Masato
Murata, Hiroshi
Nakakura, Shunsuke
Nakao, Yoshitaka
Yamashita, Takehiro
Hirasawa, Kazunori
Fujino, Yuri
Kiuchi, Yoshiaki
Asaoka, Ryo
The relationship between retinal nerve fibre layer thickness profiles and CorvisST tonometry measured biomechanical properties in young healthy subjects
title The relationship between retinal nerve fibre layer thickness profiles and CorvisST tonometry measured biomechanical properties in young healthy subjects
title_full The relationship between retinal nerve fibre layer thickness profiles and CorvisST tonometry measured biomechanical properties in young healthy subjects
title_fullStr The relationship between retinal nerve fibre layer thickness profiles and CorvisST tonometry measured biomechanical properties in young healthy subjects
title_full_unstemmed The relationship between retinal nerve fibre layer thickness profiles and CorvisST tonometry measured biomechanical properties in young healthy subjects
title_short The relationship between retinal nerve fibre layer thickness profiles and CorvisST tonometry measured biomechanical properties in young healthy subjects
title_sort relationship between retinal nerve fibre layer thickness profiles and corvisst tonometry measured biomechanical properties in young healthy subjects
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428286/
https://www.ncbi.nlm.nih.gov/pubmed/28341831
http://dx.doi.org/10.1038/s41598-017-00345-y
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