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Exploring the Association Between Demographics, SLC30A8 Genotype, and Human Islet Content of Zinc, Cadmium, Copper, Iron, Manganese and Nickel

A widely prevalent single nucleotide polymorphism, rs13266634 in the SLC30A8 gene encoding the zinc transporter ZnT8, is associated with an increased risk for T2DM. ZnT8 is mostly expressed in pancreatic insulin-producing islets of Langerhans. The effect of this variant on the divalent metal profile...

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Detalles Bibliográficos
Autores principales:	Wong, Winifred P., Allen, Norrina B., Meyers, Matthew S., Link, Emma O., Zhang, Xiaomin, MacRenaris, Keith W., El Muayed, Malek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428289/ https://www.ncbi.nlm.nih.gov/pubmed/28352089 http://dx.doi.org/10.1038/s41598-017-00394-3

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