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Poly(ADP-ribosylation) is present in murine sciatic nerve fibers and is altered in a Charcot-Marie-Tooth-1E neurodegenerative model

BACKGROUND: Poly-ADP-ribose (PAR) is a polymer synthesized by poly-ADP-ribose polymerases (PARPs) as a postranslational protein modification and catabolized mainly by poly-ADP-ribose glycohydrolase (PARG). In spite of the existence of cytoplasmic PARPs and PARG, research has been focused on nuclear...

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Detalles Bibliográficos
Autores principales: Lafon Hughes, Laura I., Romeo Cardeillac, Carlos J., Cal Castillo, Karina B., Vilchez Larrea, Salomé C., Sotelo Sosa, José R., Folle Ungo, Gustavo A., Fernández Villamil, Silvia H., Kun González, Alejandra E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428328/
https://www.ncbi.nlm.nih.gov/pubmed/28503382
http://dx.doi.org/10.7717/peerj.3318