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Poly(ADP-ribosylation) is present in murine sciatic nerve fibers and is altered in a Charcot-Marie-Tooth-1E neurodegenerative model
BACKGROUND: Poly-ADP-ribose (PAR) is a polymer synthesized by poly-ADP-ribose polymerases (PARPs) as a postranslational protein modification and catabolized mainly by poly-ADP-ribose glycohydrolase (PARG). In spite of the existence of cytoplasmic PARPs and PARG, research has been focused on nuclear...
Autores principales: | Lafon Hughes, Laura I., Romeo Cardeillac, Carlos J., Cal Castillo, Karina B., Vilchez Larrea, Salomé C., Sotelo Sosa, José R., Folle Ungo, Gustavo A., Fernández Villamil, Silvia H., Kun González, Alejandra E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428328/ https://www.ncbi.nlm.nih.gov/pubmed/28503382 http://dx.doi.org/10.7717/peerj.3318 |
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