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Medaka insulin-like growth factor-2 supports self-renewal of the embryonic stem cell line and blastomeres in vitro
Insulin-like growth factors (IGFs) regulate diverse processes including energy metabolism, cell proliferation and embryonic development. They activate the IGF signaling pathway via binding to cell surface receptors. Here we report an essential role of IGF2 in maintaining the pluripotency of embryoni...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428361/ https://www.ncbi.nlm.nih.gov/pubmed/28250437 http://dx.doi.org/10.1038/s41598-017-00094-y |