Immune evasion of Borrelia miyamotoi: CbiA, a novel outer surface protein exhibiting complement binding and inactivating properties

Borrelia (B.) miyamotoi, an emerging tick-borne relapsing fever spirochete, resists complement-mediated killing. To decipher the molecular principles of immune evasion, we sought to identify determinants contributing to complement resistance. Employing bioinformatics, we identified a gene encoding f...

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Detalles Bibliográficos
Autores principales: Röttgerding, Florian, Wagemakers, Alex, Koetsveld, Joris, Fingerle, Volker, Kirschfink, Michael, Hovius, Joppe W., Zipfel, Peter F., Wallich, Reinhard, Kraiczy, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428533/
https://www.ncbi.nlm.nih.gov/pubmed/28331202
http://dx.doi.org/10.1038/s41598-017-00412-4

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