Cargando…
Telmisartan suppresses cardiac hypertrophy by inhibiting cardiomyocyte apoptosis via the NFAT/ANP/BNP signaling pathway
Telmisartan, a type of angiotensin II (Ang II) receptor inhibitor, is a common agent used to treat hypertension in the clinic. Hypertension increases cardiac afterload and promotes cardiac hypertrophy. However, the ventricular Ang II receptor may be activated in the absence of hypertension. Therefor...
Autores principales: | Li, Xiurong, Lan, Yuhuai, Wang, Yan, Nie, Minghao, Lu, Yanhong, Zhao, Eryang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428554/ https://www.ncbi.nlm.nih.gov/pubmed/28447738 http://dx.doi.org/10.3892/mmr.2017.6318 |
Ejemplares similares
-
NULP1 Alleviates Cardiac Hypertrophy by Suppressing NFAT3 Transcriptional Activity
por: Zhang, Xin, et al.
Publicado: (2020) -
Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy
por: Lunde, Ida G., et al.
Publicado: (2022) -
A NFAT decoy approach to inhibit cardiac hypertrophy
por: Heineke, Joerg
Publicado: (2021) -
How does NFAT3 regulate the occurrence of cardiac hypertrophy?
por: Hui, Wang, et al.
Publicado: (2023) -
Sumoylation-independent activation of Calcineurin-NFAT-signaling via SUMO2 mediates cardiomyocyte hypertrophy
por: Bernt, Alexander, et al.
Publicado: (2016)