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Eye bank prepared versus surgeon cut endothelial graft tissue for Descemet membrane endothelial keratoplasty: An observational study
The purpose of this article is to examine outcomes of Descemet membrane endothelial keratoplasty (DMEK) performed with cornea bank (CB) prestripped tissue and surgeon stripped tissue (SST). This retrospective study examined subjects who underwent DMEK with CB or surgeon prepared tissue for Fuchs end...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428626/ https://www.ncbi.nlm.nih.gov/pubmed/28489792 http://dx.doi.org/10.1097/MD.0000000000006885 |
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author | Regnier, Marie Auxenfans, Céline Maucort-Boulch, Delphine Marty, Anne-Sophie Damour, Odile Burillon, Carole Kocaba, Viridiana |
author_facet | Regnier, Marie Auxenfans, Céline Maucort-Boulch, Delphine Marty, Anne-Sophie Damour, Odile Burillon, Carole Kocaba, Viridiana |
author_sort | Regnier, Marie |
collection | PubMed |
description | The purpose of this article is to examine outcomes of Descemet membrane endothelial keratoplasty (DMEK) performed with cornea bank (CB) prestripped tissue and surgeon stripped tissue (SST). This retrospective study examined subjects who underwent DMEK with CB or surgeon prepared tissue for Fuchs endothelial corneal dystrophy. Best-corrected visual acuity (BCVA), corneal thickness, endothelial cell count (ECC), and complications were examined before and throughout a 6-month postoperative period. Eleven CB and 22 SST subjects were included. Six months after surgery, BCVA was 20/20 or better in 36.4% of CB and 22.7% of SST subjects (P = .43). Median logMAR BCVA was 0.10 (0.00–0.20, 20/25) in group CB and 0.10 (0.10–0.30, 20/25) in group SST. Median preoperative corneal thickness was 614.0 μm (577.5–662.0 μm) and 658.0 μm (606.0–689.0 μm) in CB and SST subjects, respectively (P = .37). Six months after surgery, median corneal thickness was lower in the CB group (571.0 μm [478.0–592.0 μm]), than in the SST group (576.0 μm [531.0–607.0 μm], P = .02). At 6 months, median ECC was 1500.0 cell/mm(2) (1321.5–2049.0 cell/mm(2), 41% decrease) in group CB and 1403.0 cell/mm(2) (972.5–2010.7 cell/mm(2), 46% decrease) in group SST (P = .70). Rebubbling was required in 5 CB (45.5%) and 15 SST (68.2%) subjects (P = .39). Fuchs’ dystrophy patients have good anatomic and functional DMEK results. Similar outcomes and complication rates occurred with eye bank and surgeon prepared donor tissue. |
format | Online Article Text |
id | pubmed-5428626 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-54286262017-05-17 Eye bank prepared versus surgeon cut endothelial graft tissue for Descemet membrane endothelial keratoplasty: An observational study Regnier, Marie Auxenfans, Céline Maucort-Boulch, Delphine Marty, Anne-Sophie Damour, Odile Burillon, Carole Kocaba, Viridiana Medicine (Baltimore) 5800 The purpose of this article is to examine outcomes of Descemet membrane endothelial keratoplasty (DMEK) performed with cornea bank (CB) prestripped tissue and surgeon stripped tissue (SST). This retrospective study examined subjects who underwent DMEK with CB or surgeon prepared tissue for Fuchs endothelial corneal dystrophy. Best-corrected visual acuity (BCVA), corneal thickness, endothelial cell count (ECC), and complications were examined before and throughout a 6-month postoperative period. Eleven CB and 22 SST subjects were included. Six months after surgery, BCVA was 20/20 or better in 36.4% of CB and 22.7% of SST subjects (P = .43). Median logMAR BCVA was 0.10 (0.00–0.20, 20/25) in group CB and 0.10 (0.10–0.30, 20/25) in group SST. Median preoperative corneal thickness was 614.0 μm (577.5–662.0 μm) and 658.0 μm (606.0–689.0 μm) in CB and SST subjects, respectively (P = .37). Six months after surgery, median corneal thickness was lower in the CB group (571.0 μm [478.0–592.0 μm]), than in the SST group (576.0 μm [531.0–607.0 μm], P = .02). At 6 months, median ECC was 1500.0 cell/mm(2) (1321.5–2049.0 cell/mm(2), 41% decrease) in group CB and 1403.0 cell/mm(2) (972.5–2010.7 cell/mm(2), 46% decrease) in group SST (P = .70). Rebubbling was required in 5 CB (45.5%) and 15 SST (68.2%) subjects (P = .39). Fuchs’ dystrophy patients have good anatomic and functional DMEK results. Similar outcomes and complication rates occurred with eye bank and surgeon prepared donor tissue. Wolters Kluwer Health 2017-05-12 /pmc/articles/PMC5428626/ /pubmed/28489792 http://dx.doi.org/10.1097/MD.0000000000006885 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 5800 Regnier, Marie Auxenfans, Céline Maucort-Boulch, Delphine Marty, Anne-Sophie Damour, Odile Burillon, Carole Kocaba, Viridiana Eye bank prepared versus surgeon cut endothelial graft tissue for Descemet membrane endothelial keratoplasty: An observational study |
title | Eye bank prepared versus surgeon cut endothelial graft tissue for Descemet membrane endothelial keratoplasty: An observational study |
title_full | Eye bank prepared versus surgeon cut endothelial graft tissue for Descemet membrane endothelial keratoplasty: An observational study |
title_fullStr | Eye bank prepared versus surgeon cut endothelial graft tissue for Descemet membrane endothelial keratoplasty: An observational study |
title_full_unstemmed | Eye bank prepared versus surgeon cut endothelial graft tissue for Descemet membrane endothelial keratoplasty: An observational study |
title_short | Eye bank prepared versus surgeon cut endothelial graft tissue for Descemet membrane endothelial keratoplasty: An observational study |
title_sort | eye bank prepared versus surgeon cut endothelial graft tissue for descemet membrane endothelial keratoplasty: an observational study |
topic | 5800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428626/ https://www.ncbi.nlm.nih.gov/pubmed/28489792 http://dx.doi.org/10.1097/MD.0000000000006885 |
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