Enhancement of CCL2 expression and monocyte migration by CCN1 in osteoblasts through inhibiting miR-518a-5p: implication of rheumatoid arthritis therapy

Cysteine-rich 61 (Cyr61 or CCN1), a secreted protein from the CCN family, is an important proinflammatory cytokine. Migration and infiltration of mononuclear cells to inflammatory sites play a critical role in the pathogenesis of rheumatoid arthritis (RA). Monocyte chemoattractant protein-1 (MCP-1/C...

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Detalles Bibliográficos
Autores principales: Chen, Cheng-Yu, Fuh, Lih-Jyh, Huang, Chien-Chung, Hsu, Chin-Jung, Su, Chen-Ming, Liu, Shan-Chi, Lin, Yu-Min, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428676/
https://www.ncbi.nlm.nih.gov/pubmed/28341837
http://dx.doi.org/10.1038/s41598-017-00513-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428676/
https://www.ncbi.nlm.nih.gov/pubmed/28341837
http://dx.doi.org/10.1038/s41598-017-00513-0

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