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Protein tyrosine phosphatase Shp2 deficiency in podocytes attenuates lipopolysaccharide-induced proteinuria

Podocytes are specialized epithelial cells that play a significant role in maintaining the integrity of the glomerular filtration barrier and preventing urinary protein leakage. We investigated the contribution of protein tyrosine phosphatase Shp2 to lipopolysaccharide (LPS)-induced renal injury. We...

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Detalles Bibliográficos
Autores principales: Hsu, Ming-Fo, Bettaieb, Ahmed, Ito, Yoshihiro, Graham, James, Havel, Peter J., Haj, Fawaz G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428720/
https://www.ncbi.nlm.nih.gov/pubmed/28352079
http://dx.doi.org/10.1038/s41598-017-00564-3

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