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Protein tyrosine phosphatase Shp2 deficiency in podocytes attenuates lipopolysaccharide-induced proteinuria
Podocytes are specialized epithelial cells that play a significant role in maintaining the integrity of the glomerular filtration barrier and preventing urinary protein leakage. We investigated the contribution of protein tyrosine phosphatase Shp2 to lipopolysaccharide (LPS)-induced renal injury. We...
Autores principales: | Hsu, Ming-Fo, Bettaieb, Ahmed, Ito, Yoshihiro, Graham, James, Havel, Peter J., Haj, Fawaz G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428720/ https://www.ncbi.nlm.nih.gov/pubmed/28352079 http://dx.doi.org/10.1038/s41598-017-00564-3 |
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