TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents

Mutations in the gene encoding for filaggrin (FLG) are major predisposing factors for atopic dermatitis (AD). Besides genetic predisposition, immunological dysregulations considerably contribute to its pathophysiology. For example, thymic stromal lymphopoietin (TSLP) is highly expressed in lesional...

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Detalles Bibliográficos
Autores principales: Wallmeyer, Leonie, Dietert, Kristina, Sochorová, Michaela, Gruber, Achim D., Kleuser, Burkhard, Vávrová, Kateřina, Hedtrich, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428778/
https://www.ncbi.nlm.nih.gov/pubmed/28377574
http://dx.doi.org/10.1038/s41598-017-00670-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428778/
https://www.ncbi.nlm.nih.gov/pubmed/28377574
http://dx.doi.org/10.1038/s41598-017-00670-2

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