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Interplay of DNA methyltransferase 1 and EZH2 through inactivation of Stat3 contributes to β-elemene-inhibited growth of nasopharyngeal carcinoma cells

β-elemene, a compound extracted from Curcuma wenyujin plant, exhibits anticancer activity in many cancer types. However, the detailed mechanism by which β-elemene inhibits growth of nasopharyngeal carcinoma (NPC) cells remains unknown. We showed that β-elemene reduced phosphorylation of signal trans...

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Detalles Bibliográficos
Autores principales: Wu, JingJing, Tang, Qing, Yang, LiJuan, Chen, YuQing, Zheng, Fang, Hann, Swei Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428779/
https://www.ncbi.nlm.nih.gov/pubmed/28360411
http://dx.doi.org/10.1038/s41598-017-00626-6