Cargando…
Interplay of DNA methyltransferase 1 and EZH2 through inactivation of Stat3 contributes to β-elemene-inhibited growth of nasopharyngeal carcinoma cells
β-elemene, a compound extracted from Curcuma wenyujin plant, exhibits anticancer activity in many cancer types. However, the detailed mechanism by which β-elemene inhibits growth of nasopharyngeal carcinoma (NPC) cells remains unknown. We showed that β-elemene reduced phosphorylation of signal trans...
Autores principales: | Wu, JingJing, Tang, Qing, Yang, LiJuan, Chen, YuQing, Zheng, Fang, Hann, Swei Sunny |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428779/ https://www.ncbi.nlm.nih.gov/pubmed/28360411 http://dx.doi.org/10.1038/s41598-017-00626-6 |
Ejemplares similares
-
Inactivation of Stat3 and crosstalk of miRNA155-5p and FOXO3a contribute to the induction of IGFBP1 expression by beta-elemene in human lung cancer
por: Zheng, Fang, et al.
Publicado: (2018) -
β-elemene inhibited expression of DNA methyltransferase 1 through activation of ERK1/2 and AMPKα signalling pathways in human lung cancer cells: the role of Sp1
por: Zhao, ShunYu, et al.
Publicado: (2015) -
Inactivation of PI3-K/Akt and reduction of SP1 and p65 expression increase the effect of solamargine on suppressing EP4 expression in human lung cancer cells
por: Chen, YuQing, et al.
Publicado: (2015) -
Inhibition of EZH2 via activation of SAPK/JNK and reduction of p65 and DNMT1 as a novel mechanism in inhibition of human lung cancer cells by polyphyllin I
por: Li, Longmei, et al.
Publicado: (2016) -
Activation of SAPK/JNK mediated the inhibition and reciprocal interaction of DNA methyltransferase 1 and EZH2 by ursolic acid in human lung cancer cells
por: Wu, Jingjing, et al.
Publicado: (2015)