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Novel insights into the interaction of UBA5 with UFM1 via a UFM1-interacting sequence

The modification of proteins by ubiquitin-fold modifier 1 (UFM1) is implicated in many human diseases. Prior to conjugation, UFM1 undergoes activation by its cognate activating enzyme, UBA5. UBA5 is a non-canonical E1 activating enzyme that possesses an adenylation domain but lacks a distinct cystei...

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Detalles Bibliográficos
Autores principales:	Padala, Prasanth, Oweis, Walaa, Mashahreh, Bayan, Soudah, Nadine, Cohen-Kfir, Einav, Todd, Emily A., Berndsen, Christopher E., Wiener, Reuven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428781/ https://www.ncbi.nlm.nih.gov/pubmed/28360427 http://dx.doi.org/10.1038/s41598-017-00610-0

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