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Mesoporous silica nanoparticles trigger mitophagy in endothelial cells and perturb neuronal network activity in a size- and time-dependent manner

PURPOSE: Mesoporous silica nanoparticles (MSNPs) are excellent candidates for biomedical applications and drug delivery to different human body areas, the brain included. Although toxicity at cellular level has been investigated, we are still far from using MSNPs in the clinic, because the mechanism...

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Detalles Bibliográficos
Autores principales: Orlando, Antonina, Cazzaniga, Emanuela, Tringali, Maria, Gullo, Francesca, Becchetti, Andrea, Minniti, Stefania, Taraballi, Francesca, Tasciotti, Ennio, Re, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428814/
https://www.ncbi.nlm.nih.gov/pubmed/28507435
http://dx.doi.org/10.2147/IJN.S127663