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Cyclooxygenase-2 Signalling Pathway in the Cortex is Involved in the Pathophysiological Mechanisms in the Rat Model of Depression

This study was designed to investigate the effect of the cortical cyclooxygenase-2 (COX2) pathway on depressive behaviour in rats. Meloxicam, COX2 overexpressed lentivirus and COX2 RNAi lentivirus were administered to Sprague-Dawley rats subjected to chronic unpredictable mild stress (CUMS). Behavio...

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Detalles Bibliográficos
Autores principales:	Chen, Qi, Luo, Ying, Kuang, Shengnan, Yang, Yang, Tian, Xiaoyan, Ma, Jie, Mai, Shaoshan, Xue, Lai, Yang, Junqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428817/ https://www.ncbi.nlm.nih.gov/pubmed/28352129 http://dx.doi.org/10.1038/s41598-017-00609-7

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