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Overexpression of GSN could decrease inflammation and apoptosis in EAE and may enhance vitamin D therapy on EAE/MS

The decrease of gelsolin (GSN) in the blood has been reported in multiple sclerosis (MS) patients and experimental allergic encephalomyelitis (EAE) animals, but the protective effect of GSN on EAE/MS lacks of evidence. In our study, we increased the GSN level in EAE by injecting GSN-overexpress lent...

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Detalles Bibliográficos
Autores principales: Gao, Jifang, Qin, Zhaoyu, Guan, Xinyuan, Guo, Juanjuan, Wang, Huaqing, Liu, Shilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428824/
https://www.ncbi.nlm.nih.gov/pubmed/28377587
http://dx.doi.org/10.1038/s41598-017-00684-w