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Overexpression of GSN could decrease inflammation and apoptosis in EAE and may enhance vitamin D therapy on EAE/MS
The decrease of gelsolin (GSN) in the blood has been reported in multiple sclerosis (MS) patients and experimental allergic encephalomyelitis (EAE) animals, but the protective effect of GSN on EAE/MS lacks of evidence. In our study, we increased the GSN level in EAE by injecting GSN-overexpress lent...
Autores principales: | Gao, Jifang, Qin, Zhaoyu, Guan, Xinyuan, Guo, Juanjuan, Wang, Huaqing, Liu, Shilian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428824/ https://www.ncbi.nlm.nih.gov/pubmed/28377587 http://dx.doi.org/10.1038/s41598-017-00684-w |
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