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Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson’s disease model

Dysfunctional parkin due to mutations or post-translational modifications contributes to dopaminergic neurodegeneration in Parkinson’s disease (PD). Overexpression of parkin provides protection against cellular stresses and prevents dopamine cell loss in several PD animal models. Here we performed a...

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Detalles Bibliográficos
Autores principales: Ham, Sangwoo, Lee, Yun-Il, Jo, Minkyung, Kim, Hyojung, Kang, Hojin, Jo, Areum, Lee, Gum Hwa, Mo, Yun Jeong, Park, Sang Chul, Lee, Yun Song, Shin, Joo-Ho, Lee, Yunjong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428870/
https://www.ncbi.nlm.nih.gov/pubmed/28366931
http://dx.doi.org/10.1038/s41598-017-00614-w